He was born in Fort Worth, Texas; where he attended high school with Ben Hogan. He was the public address announcer at high school football games and began calling them on the radio even before he graduated. While at Texas Christian University (where he was a classmate of Sammy Baugh), he broadcast Southwest Conference football games, many of which aired on CBS Radio's College Football Roundup.
Ted Husing, CBS' main sportscaster, heard some of Saam's work and suggested that Saam apply for a job at WCCO in Minneapolis in 1934. The station asked him to do a baseball audition. While Saam had played baseball in high school, he'd never broadcast it before. However, he did well enough to get the job and soon became the station's lead sportscaster. He called the Triple A Minneapolis Millers, re-created the 1935 World Series, and called University of Minnesota football.
Moving to WCAU in Philadelphia in 1937, he called Temple, University of Pennsylvania and Villanova football games. He was soon noticed by the owners of both major league ballclubs in Philadelphia, the Athletics and the Phillies.
In 1938, Saam became the first full-time voice of the Athletics; he added the Phillies the next year and continued this double duty for 12 seasons. This was possible since both teams shared Shibe Park and almost never played at home on the same day. For most of Saam's tenure, the A's and Phillies were also-rans. He was behind the microphone for over 4,000 losses—by one estimate, the most of any baseball announcer ever. His descriptive play-by-play flair earned Saam the nickname "The Man of a Zillion Words."
After both Philadelphia teams began airing road games live in 1950, Saam was forced to drop one team since no radio station could handle the full load. He chose to drop the Phillies, since he and Athletics owner/manager Connie Mack had been longtime friends. That year's Phillies won their first National League pennant in 35 years, while the Athletics finished last. Saam and partner Claude Haring did Athletics games until the team left for Kansas City after the 1954 season.
After the Athletics moved to Kansas City, Saam returned to the Phillies in 1955. He was joined by Bill Campbell in 1962; the pair was joined by former Phillies outfielder Richie Ashburn a year later. Campbell left in 1970 and was replaced by Harry Kalas. They broadcast Phillies games until Saam's retirement in 1975. Ironically, the year after Saam retired, the Phillies won the National League East—their first postseason appearance of any kind since 1950. For this reason, Kalas and Ashburn invited Saam into the booth for the division-clinching game and let him call the last half-inning.12 Ashburn later said, "Thirty-eight years and no winner. Damn right he deserved a title."
Despite having never called a pennant or division winner in Philadelphia, Saam did call 13 no-hitters, including Jim Bunning's perfect game in 1964. He also broadcast the World Series for NBC Radio in 1959 and 1965.
Saam was also involved in Philadelphia Ramblers (Eastern Hockey League) games as a radio play-by-play broadcaster. On January 8, 1961, the Ramblers visited the New York Rovers at the Long Island Arena with Saam broadcasting the 3rd period and overtime back to Philadelphia.
Saam was known for occasional slip-ups on the air. For example, he once opened a game by saying, "Hello, Byrum Saam, this is everybody speaking." Prior to Game 5 of the 1959 World Series, when Mel Allen introduced the NBC Radio audience to "amiable, affable, able Byrum Saam", a distracted Saam unthinkingly replied, "Right you are, Mel." Once Saam created a beheading when Alex Johnson, the Phillies' left fielder, chased a fly ball: "Alex Johnson is going back. He's going back, back. His head hits the wall. He reaches down, picks it up, and throws into second base."3
In 1990, Byrum Saam was awarded the Ford Frick Award by the Baseball Hall of Fame for excellence in broadcasting. Ashburn was later honored by the Hall of Fame as a player, and Kalas won the Frick Award in 2002.
By Saam was inducted into the Philadelphia Broadcast Pioneers Hall of Fame in 1993.
Saam died in 2000 in Devon, Pennsylvania.