|Drawing of colon seen from front (descending colon coloured blue)|
|Front of abdomen, showing surface markings for liver, stomach, and great intestine (descending colon visible at center right, in blue)|
|Gray's||subject #249 1181|
|Artery||Left colic artery|
The descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon and thereby part of the large intestine. The function of the descending colon in the digestive system is to store food that will be emptied into the rectum.
The descending colon begins at the splenic flexure at at the upper left part of the abdomen. It passes downward through the left hypochondrium and lumbar regions, along the lateral border of the left kidney and end at the lower left part of the abdomen where it is continues as the sigmoid colon. It is retroperitoneal in two-thirds of humans. In the other third, it has a (usually short) mesentery. The arterial supply comes via the left colic artery.
While the first part of the large intestine is responsible for the absorption of water and other substances from the chyme, the main function of the descending colon is to store waste until it can be removed from the body in solid form, when a person has a bowel movement. The stools gradually solidify as they move along into the descending colon.1
There are several diseases associated with the descending colon. Among the most common are the irritable and inflammatory bowel diseases (such as ulcerative colitis or Crohn’s disease) and colon cancer.
Ulcerative colitis can affect any part of the colon (and other mucosa, such as the mouth), but when it affects the descending colon, it is called left-sided colitis. Inflammation and ulcers on the lining of the intestine mark its presence. Symptoms of ulcerative colitis include diarrhea, bleeding, fever, abdominal pain, too much mucus in fecal material, and appetite and weight loss. Treatment methods can vary widely, ranging from changes in diet to drug therapy to corrective surgery, depending on the severity of the condition and the overall health of the patient.
When a person has Crohn’s disease or Crohn’s colitis, they have lesions on the tissues of the intestine; this makes it hard for the intestine to absorb water and salt. The symptoms which may develop from this disease include abdominal pain, diarrhea or constipation, nausea and vomiting, fever, blood in the stool, weight loss, abscesses and fatigue. There is no cure for Crohn’s disease although many treatments are available. Symptomatic treatment with antidiarrhoeals is common in low level cases where the inflammation is reasonably under control. Steroid and/or sulphasalazine treatment are usually the first line of drug based management, although newer drugs along the TNF inhibitor line (such as infliximab and adalimumab) are becoming more widespread in the treatment of inflammatory colonic conditions. Diet and lifestyle changes can also be useful, as stress may exacerbate inflammatory processes.
Cancer of the descending colon is the most serious of the diseases. A person can have colon cancer yet have no symptoms in the early stages. As such, regular colorectal examinations or fecal occult blood testing are necessary for catching the disease in its early stages. However, there are some signs that can indicate colon cancer; they include abrupt changes in bowel habits, bleeding from the rectum, black stools, frequent constipation, and mucus in the stools. Treatment options depend on the stage of the cancer and the overall health of the patient.
- The Function Of The Colon Retrieved on 2010-01-21