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A directorate-general is a branch of an administration dedicated to a specific field of expertise.
- The European Commission: Commission Directorates-General are each headed by a director-general, who reports to the European Commissioner in charge of (i.e. politically responsible for) the corresponding policy area;
- The European Patent Office: EPO Directorates-General;
- The Secretariat of the European Parliament: Parliament Directorates-General.