|Systematic (IUPAC) name|
|Pregnancy cat.||D (US)|
|Legal status||℞-only (US)|
|Mol. mass||497.494 g/mol|
| (what is this?)
Idarubicin (pron.: //) or 4-demethoxydaunorubicin is an anthracycline antileukemic drug. It inserts itself into DNA and prevents DNA from unwinding by interfering with the enzyme topoisomerase II. It is an analog of daunorubicin, but the absence of a methoxy group increases its fat solubility and cellular uptake. 1
It belongs to the family of drugs called antitumor antibiotics.
It is distributed under the trade names Zavedos (UK) and Idamycin (USA).
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