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WNPX's transmitter is located at Whites Creek, Tennessee, 7 miles (11 km) north of Nashville. The station also utilizes a translator on WNPX-LP channel 20, also located at Whites Creek.
WNPX is affiliated with the Ion Television network (formerly PAX-TV and i). The callsign is derived from "Nashville PaX."
The station signed on January 23, 1989 as WMTT an independent station serving Cookeville. WMTT changed its call sign to WKZX in 1994 and became an affiliate of the WB Television Network in 1995. The station moved and upgraded its transmitter to begin focusing on the Nashville market and became WNPX in 1998, broadcasting Pax programming.